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Overview of Tissue Healing Process

Healing is a complex process that can be defined as the process in which dead or injured tissue is replaced by living tissue that consists of the stages of the three broad stages of inflammation, fibroplasia or proliferation, and scar formation (A.T. Still University, 2017) The stages are not isolated incidents. Instead they overlap and happen simultaneously.

Before the healing process begins hemostasis, the process of which the body controls bleeding, occurs. In hemostasis, blood vessels vasoconstrict and begin forming blood clots composed of collagen, thrombin, and fibronectin, which act as a type of scaffolding to prevent pathogens from entering the cell, stimulates the release of cytokines and growth factors from the platelets, which initiates the inflammation process (Rand & Gelhorn, 2016) The Inflammation is the first stage of healing and happens hours after injury and can last for several months if the injury is mismanaged. The goal of inflammation is to eliminate any pathogens and remove damaged tissue components. It is the first response to injury and in it pathogens are destroyed and is vital to tissue repair. Pro-inflammatory molecules that are released increase vasodilation, permeability, and the migration of cells (Rand & Gelhorn, 2016). This decreases lymphatic drainage and forms the swelling associated with inflammation. Pathogens and dead cells are cl